Hasta la vista, Firefox
It's not like Safari is that bad, anymore. It has tabbed browsing. It doesn't screw up so many sites anymore. And if you have to have a Mozilla-based browser, Camino is pretty darn good. I've been using it for a couple of weeks now, and I like it a lot. It uses the Keychain to store web passwords, which is really nice: it makes me feel much more secure about my important passwords, and I can find them easily if I want them for another browser. Plus, it has an "update stored password" function if you're trying to log onto a site you haven't accessed for awhile, and your first password guess turns out to be wrong: it simply notices that you've typed a different password the second time, and offers to update. Nice.
And it looks pretty nice too.
Of course I'll keep Firefox on the machine, to check the appearance of my web pages, etc, but at the moment I mostly use Camino and Safari for actual web browsing. No more painfully-slow Mac. No more periodically shutting down Firefox just to get it to let go of all the memory it hogged. No more worrying about opening Photoshop with Firefox running. Oh joy!